Time-Course of Body Temperature and Postoprative Complication in Whole Body Hyperthermotherapy

SUMMARY Whole body hyperthermotherapy was applied to 15 cases of 12 patients as treatment for malignant tumor, by means of extracorporeal circulation with 12 cases, including 7 cases of the V-A bypass and 5 cases of the A-V bypass, as well as surface warrriing with 3 cases. The therapeutic temperature of 41 °C or above was maintained on all of them for 2 hours and 57 minutes on an average. The longer time was required for body temperature elevation by extracorporeal circulation, while no difference was noted in both ways for lowerling body temperature. In addition to 5 cases of paralysis on the femoal area for the extracorporal circuit, each one case of herpes zoster, renal failure, heart failure and posttransfusion hepatitis was noted as postoprative complication by the extracorporeal circulation. As to the renal function more than a half of them showed increase of serum BUN and serum creatinine. Referring to blood examination, thrombocytopemia and leukocytopenia were noted on nearly all of those with extracorporal circulation. The therapeutic effect was determinated positively with 4 patients.